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Canada

What 82 common medicines are sold as in Canada, and whether you can buy them over the counter. Take extra care with anything controlled or banned if you're bringing your own.

Entry summary

  • Controlled (Rx)6
  • Rx only41
  • OTC / Rx4
  • No Rx: Ask Pharmacist4
  • OTC23
  • Unavailable4
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MedicineAsk forStatus
ParacetamolAnalgesic / antipyreticAsk forTylenolOTC
IbuprofenNSAIDAsk forAdvilOTC
LoratadineAntihistamine, non-sedatingAsk forClaritinOTC
CetirizineAntihistamine, non-sedatingAsk forReactineOTC / Rx

Regular 5 mg and 10 mg Reactine is sold without a prescription; the 20 mg tablet is prescription-only.

DiphenhydramineAntihistamine, sedatingAsk forBenadrylOTC
LoperamideAntidiarrhealAsk forImodiumOTC
OmeprazoleProton pump inhibitorAsk forLosecRx only
PseudoephedrineDecongestantAsk forSudafedNo Rx: Ask Pharmacist
MelatoninSleep aid / hormoneAsk forSold as a "natural health product"OTC / Rx

No prescription needed for adults (18 and over); for anyone under 18 it needs a prescription.

DimenhydrinateAntiemetic / motion sicknessAsk forGravolOTC
AmoxicillinAntibiotic, penicillinAsk forSold generic (formerly Amoxil)Rx only
MetforminAntidiabetic, biguanideAsk forGlucophage (mostly sold generic)Rx only
SertralineSSRI antidepressantAsk forZoloftRx only
SalbutamolBronchodilator, inhaledAsk forVentolinRx only
AtorvastatinStatin (cholesterol)Ask forLipitor (mostly sold generic now)Rx only
LevothyroxineThyroid hormone (hypothyroidism)Ask forSynthroidRx only
LisinoprilACE inhibitor (blood pressure)Ask forZestril (mostly sold generic)Rx only
AmlodipineCalcium channel blocker (blood pressure)Ask forNorvasc (mostly sold generic)Rx only
MetoprololBeta blocker (blood pressure/heart)Ask forSold generic (formerly Lopresor)Rx only
LosartanARB (blood pressure)Ask forCozaar (mostly sold generic)Rx only

The Cozaar brand is still sold in Canada.

GabapentinNerve pain / anticonvulsantAsk forNeurontin (mostly sold generic)Rx only
RosuvastatinStatin (cholesterol)Ask forCrestorRx only
PantoprazoleProton pump inhibitorAsk forPantolocRx only

Still sold under this brand in Canada.

EscitalopramSSRI antidepressantAsk forCipralexRx only
Amphetamine / DextroamphetamineStimulant (ADHD), controlled substanceAsk forAdderall XRControlled (Rx)
HydrochlorothiazideDiuretic (blood pressure)Ask forSold genericRx only
BupropionAtypical antidepressant / smoking cessationAsk forWellbutrinRx only
FluoxetineSSRI antidepressantAsk forSold genericRx only

The Prozac brand was discontinued in Canada. All its registrations (DINs) are cancelled, the last in 2024.

SemaglutideGLP-1 agonist (diabetes/weight)Ask forOzempic / WegovyRx only
MontelukastLeukotriene modifier (asthma/allergy)Ask forSingulairRx only
TrazodoneAntidepressant (commonly used off-label for sleep)Ask forSold genericRx only

Desyrel brand was discontinued in Canada (cancelled 2010).

SimvastatinStatin (cholesterol)Ask forZocorRx only
TamsulosinAlpha blocker (enlarged prostate)Ask forSold genericRx only

The Flomax brand was discontinued in Canada. Its last registration (Flomax CR) was cancelled in 2024.

Hydrocodone / Paracetamol combinationOpioid analgesic combination, controlled substanceAsk forSold genericControlled (Rx)

Tightly controlled.

FluticasoneCorticosteroid (nasal spray / inhaler)Ask forFlonase (nasal spray, OTC) / Flovent (inhaler, Rx)OTC / Rx

The Flonase allergy nasal spray is sold without a prescription; fluticasone inhalers for asthma are prescription-only.

MeloxicamNSAID (arthritis)Ask forSold generic (formerly Mobicox)Rx only
ApixabanAnticoagulant (blood thinner)Ask forEliquisRx only
FurosemideLoop diureticAsk forSold genericRx only

Lasix brand was discontinued in Canada decades ago (cancelled 1997).

Insulin GlargineLong-acting insulinAsk forLantusRx only
Insulin LisproRapid-acting insulinAsk forHumalog / AdmelogRx only
Insulin AspartRapid-acting insulinAsk forNovoRapid / FiaspRx only
Insulin Human (Regular)Short-acting insulinAsk forHumulin R / Novolin ge TorontoNo Rx: Ask Pharmacist

Human insulin does not need a prescription in Canada: a pharmacist can supply it after a consultation. Newer insulins need one.

Insulin Isophane (NPH)Intermediate-acting insulinAsk forHumulin N / Novolin ge NPHNo Rx: Ask Pharmacist

Human insulin does not need a prescription in Canada: a pharmacist can supply it after a consultation. Newer insulins need one.

Insulin DetemirLong-acting insulinAsk forNot sold hereUnavailable

Levemir is no longer sold in Canada. Other long-acting insulins sold here: glargine (Lantus) and degludec (Tresiba).

Insulin DegludecLong-acting insulinAsk forTresibaRx only
DuloxetineSNRI antidepressantAsk forSold genericRx only

Cymbalta brand was discontinued in Canada recently (cancelled 2024).

FamotidineH2 blocker (acid reflux)Ask forPepcidOTC
EmpagliflozinSGLT2 inhibitor (diabetes)Ask forJardianceRx only
CarvedilolBeta blocker (heart failure / blood pressure)Ask forSold genericRx only

Coreg brand was discontinued in Canada (cancelled 2006).

TramadolOpioid analgesic, controlled substanceAsk forSold genericControlled (Rx)
AlprazolamBenzodiazepine (anxiety), controlled substanceAsk forXanaxControlled (Rx)

Still sold under this brand in Canada. Scheduled as a Targeted Substance (CDSA IV).

PrednisoneCorticosteroid (anti-inflammatory)Ask forWinpredRx only
ClopidogrelAntiplatelet (blood thinner)Ask forPlavixRx only

Still sold under this brand in Canada.

Acetylsalicylic acid (Aspirin)NSAID / antiplateletAsk forAspirinOTC
OxycodoneOpioid analgesic, controlled substanceAsk forOxyNEOControlled (Rx)

Original OxyContin was withdrawn from the Canadian market in 2012 and replaced by tamper-resistant OxyNEO. The Percocet brand (oxycodone/acetaminophen) was cancelled in 2017; that combination is sold generically.

MethylphenidateStimulant (ADHD), controlled substanceAsk forConcertaControlled (Rx)
NaproxenNSAIDAsk forAleveOTC
Diclofenac (topical gel)NSAID, topical (pain-relief gel)Ask forVoltaren EmulgelOTC
FexofenadineAntihistamine, non-sedatingAsk forAllegraOTC
GuaifenesinExpectorant (chesty cough)Ask forMucinex / RobitussinOTC
DextromethorphanCough suppressant (dry cough)Ask forRobitussin DMOTC

Robitussin DM also contains guaifenesin. Dextromethorphan is in most Canadian multi-symptom cold remedies.

Oxymetazoline (nasal spray)Nasal decongestant sprayAsk forDrixoralOTC
Bismuth subsalicylateUpset stomach / traveler’s diarrheaAsk forPepto-BismolOTC
Calcium carbonate (antacid)Antacid (heartburn)Ask forTumsOTC
SimeticoneAnti-gas (bloating)Ask forGas-X / OvolOTC
Oral rehydration saltsRehydration (diarrhea, heat, vomiting)Ask forPedialyteOTC

No prescription needed. Often classed as a supplement or food rather than a medicine, so brands vary and it may be shelved away from the pharmacy counter.

BisacodylLaxative, stimulantAsk forDulcolaxOTC
Polyethylene glycol 3350 (macrogol)Laxative, osmoticAsk forRestoraLAX / Lax-A-DayOTC
MeclozineAntiemetic / motion sicknessAsk forNot sold hereUnavailable

Gravol (dimenhydrinate) covers this use.

Hydrocortisone (cream)Mild steroid cream (itch, rash, bites)Ask forSold generic ("hydrocortisone cream")OTC / Rx

Creams up to 1% are sold without a prescription; anything stronger needs one, as in the US.

ClotrimazoleAntifungal cream (athlete’s foot, yeast)Ask forCanestenOTC
Bacitracin / Neomycin / Polymyxin B (antibiotic ointment)Topical antibiotic (cuts and scrapes)Ask forPolysporinOTC
DoxylamineSleep aid (sedating antihistamine)Ask forNot sold hereUnavailable

It is found in nighttime cold remedies such as NyQuil. Unisom in Canada is a different medicine (diphenhydramine). Doxylamine with vitamin B6 is prescription-only, for pregnancy nausea.

Levonorgestrel (emergency contraception)Emergency contraceptiveAsk forPlan BOTC
Atovaquone / ProguanilAntimalarial (prevention)Ask forMalaroneRx only
DoxycyclineAntibiotic, tetracycline (also malaria prevention)Ask forSold genericRx only
AzithromycinAntibiotic, macrolide (traveler’s diarrhea)Ask forSold generic (formerly Zithromax)Rx only
CiprofloxacinAntibiotic, fluoroquinolone (traveler’s diarrhea)Ask forCiproRx only
AcetazolamideAltitude sickness preventionAsk forSold genericRx only
Scopolamine (motion-sickness patch)Antiemetic patch (motion sickness)Ask forNot sold hereUnavailable

No scopolamine patch is currently marketed in Canada (Transderm-V is no longer listed). Bring patches from home.

OndansetronAntiemetic (nausea and vomiting)Ask forSold generic (formerly Zofran)Rx only
Epinephrine (adrenaline auto-injector)Emergency treatment for severe allergic reactionsAsk forEpiPenNo Rx: Ask Pharmacist