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Destination · MX

Mexico

What 82 common medicines are sold as in Mexico, and whether you can buy them over the counter. Take extra care with anything controlled or banned if you're bringing your own.

Entry summary

  • Banned: Do Not Bring1
  • Controlled (Rx)6
  • Rx only47
  • OTC / Rx7
  • No Rx: Ask Pharmacist2
  • OTC16
  • Unavailable3

In Mexico, many pharmacies have a doctor’s office next door that can examine you and write a prescription on the spot for a small fee. So prescription medicines for everyday problems are easy to get without your own doctor.

Be careful buying antibiotics and opioid painkillers in Mexico. Counterfeit and substandard products are a known risk, because manufacturing and supply are not policed as tightly as in the US. Where you can, get these from your own pharmacy before you travel.

Search within Mexico
MedicineAsk forStatus
ParacetamolAnalgesic / antipyreticAsk forTempra / TylenolOTC
IbuprofenNSAIDAsk forMotrinGeneric name here: IbuprofenoOTC / Rx

Some strengths need a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

LoratadineAntihistamine, non-sedatingAsk forClarityneGeneric name here: LoratadinaOTC
CetirizineAntihistamine, non-sedatingAsk forZyrtecGeneric name here: CetirizinaOTC
DiphenhydramineAntihistamine, sedatingAsk forBenadrylGeneric name here: DifenhidraminaOTC
LoperamideAntidiarrhealAsk forImodiumGeneric name here: LoperamidaRx only

Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

OmeprazoleProton pump inhibitorAsk forLosecOTC
PseudoephedrineDecongestantAsk forNot sold hereBanned: Do Not Bring

Banned since 2008. Mexico was the first North American country to prohibit pseudoephedrine outright.

MelatoninSleep aid / hormoneAsk forSold as a supplementGeneric name here: MelatoninaOTC / Rx

Some products are registered as prescription-only.

DimenhydrinateAntiemetic / motion sicknessAsk forDramamineGeneric name here: DimenhidrinatoOTC
AmoxicillinAntibiotic, penicillinAsk forAmoxicilinaRx only

Formally Rx-only nationwide since August 25, 2010, though enforcement varies by pharmacy, especially near the border. Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

MetforminAntidiabetic, biguanideAsk forGlucophageGeneric name here: MetforminaRx only
SertralineSSRI antidepressantAsk forAltrulineGeneric name here: SertralinaRx only
SalbutamolBronchodilator, inhaledAsk forVentolin (salbutamol)Rx only

Called salbutamol in Mexico. Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

AtorvastatinStatin (cholesterol)Ask forLipitorGeneric name here: AtorvastatinaRx only
LevothyroxineThyroid hormone (hypothyroidism)Ask forEutirox / SynthroidGeneric name here: LevotiroxinaRx only
LisinoprilACE inhibitor (blood pressure)Ask forZestrilRx only
AmlodipineCalcium channel blocker (blood pressure)Ask forNorvasGeneric name here: AmlodipinoRx only
MetoprololBeta blocker (blood pressure/heart)Ask forLopresorRx only
LosartanARB (blood pressure)Ask forCozaarRx only
GabapentinNerve pain / anticonvulsantAsk forNeurontinGeneric name here: GabapentinaRx only
RosuvastatinStatin (cholesterol)Ask forCrestorGeneric name here: RosuvastatinaRx only
PantoprazoleProton pump inhibitorAsk forPantoprazolRx only
EscitalopramSSRI antidepressantAsk forLexaproRx only
Amphetamine / DextroamphetamineStimulant (ADHD), controlled substanceAsk forVyvanse (lisdexamfetamine)Generic name here: LisdexanfetaminaControlled (Rx)

Adderall itself is not registered in Mexico. The registered medicine in this family is lisdexamfetamine (Vyvanse), a controlled psychotropic that needs a special barcoded prescription.

Source: gob.mx ↗
HydrochlorothiazideDiuretic (blood pressure)Ask forHidroclorotiazidaRx only
BupropionAtypical antidepressant / smoking cessationAsk forWellbutrinRx only

Classed as a controlled psychotropic in Mexico. If you bring your own, keep it in the original labeled bottle and be ready to show it. Officially it should be declared at customs.

FluoxetineSSRI antidepressantAsk forSold generic as "Fluoxetina"Rx only

The Prozac brand is no longer registered in Mexico.

SemaglutideGLP-1 agonist (diabetes/weight)Ask forOzempicGeneric name here: SemaglutidaRx only
MontelukastLeukotriene modifier (asthma/allergy)Ask forSingulairRx only
TrazodoneAntidepressant (commonly used off-label for sleep)Ask forSiderilGeneric name here: TrazodonaRx only

Sideril is the trazodone brand sold in Mexico. Trittico was not found there.

Source: vademecum.es ↗
SimvastatinStatin (cholesterol)Ask forSold generic as "Simvastatina"Rx only

The Zocor brand is no longer registered in Mexico.

TamsulosinAlpha blocker (enlarged prostate)Ask forSold generic as "Tamsulosina"Rx only

The Secotex brand is no longer registered in Mexico.

Hydrocodone / Paracetamol combinationOpioid analgesic combination, controlled substanceAsk forSold generic as "Hidrocodona" in some pharmaciesControlled (Rx)

The Doloff brand is not sold in Mexico, and no hydrocodone product is in the register file, though some pharmacies stock generics. Controlled: needs a special prescription. Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

Source: fahorro.com ↗
FluticasoneCorticosteroid (nasal spray / inhaler)Ask forFlixonaseGeneric name here: FluticasonaNo Rx: Ask Pharmacist

Sold as a free-sale (libre venta) product in Mexican pharmacies.

MeloxicamNSAID (arthritis)Ask forSold generic as "Meloxicam"Rx only

The Mobic brand is no longer registered in Mexico. Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

ApixabanAnticoagulant (blood thinner)Ask forElicuisRx only
FurosemideLoop diureticAsk forLasixGeneric name here: FurosemidaRx only
Insulin GlargineLong-acting insulinAsk forLantusGeneric name here: Insulina glarginaRx only
Insulin LisproRapid-acting insulinAsk forHumalogGeneric name here: Insulina lisproRx only
Insulin AspartRapid-acting insulinAsk forNovoRapidGeneric name here: Insulina aspartaRx only
Insulin Human (Regular)Short-acting insulinAsk forNovolin R / Insulex RGeneric name here: Insulina humana (rápida)Rx only
Insulin Isophane (NPH)Intermediate-acting insulinAsk forHumulin NGeneric name here: Insulina humana isófana (NPH)Rx only
Insulin DetemirLong-acting insulinAsk forLevemirGeneric name here: Insulina detemirRx only

The maker is withdrawing Levemir worldwide, so stock may be limited. Other long-acting insulins sold here: glargine (Lantus) and degludec (Tresiba).

Insulin DegludecLong-acting insulinAsk forTresibaGeneric name here: Insulina degludecRx only
DuloxetineSNRI antidepressantAsk forSold generic as "Duloxetina"Rx only

The Cymbalta brand is no longer registered in Mexico.

Source: fahorro.com ↗
FamotidineH2 blocker (acid reflux)Ask forFacidex / DuraterGeneric name here: FamotidinaOTC / Rx

Some strengths need a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

EmpagliflozinSGLT2 inhibitor (diabetes)Ask forJardianzGeneric name here: EmpagliflozinaRx only
CarvedilolBeta blocker (heart failure / blood pressure)Ask forDilatrendRx only

Sold by Roche through major Mexican pharmacy chains. Germany has discontinued the same brand.

TramadolOpioid analgesic, controlled substanceAsk forTradol (or generic tramadol)Controlled (Rx)

As of 14 July 2026, Mexico reclassified tramadol under Article 245 Section III, roughly equivalent to a US Schedule IV drug. An ordinary prescription from any licensed physician is enough (no special barcode pad needed), but pharmacies must keep the prescription after 3 fills. Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

Source: gob.mx ↗
AlprazolamBenzodiazepine (anxiety), controlled substanceAsk forTafilControlled (Rx)
PrednisoneCorticosteroid (anti-inflammatory)Ask forMeticortenGeneric name here: PrednisonaRx only
ClopidogrelAntiplatelet (blood thinner)Ask forPlavixRx only
Acetylsalicylic acid (Aspirin)NSAID / antiplateletAsk forAspirinaGeneric name here: Ácido acetilsalicílicoOTC / Rx

Some strengths need a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

OxycodoneOpioid analgesic, controlled substanceAsk forEndocodilGeneric name here: OxicodonaControlled (Rx)

Controlled substance requiring special prescription forms. The OxyContin brand is no longer registered in Mexico. Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

MethylphenidateStimulant (ADHD), controlled substanceAsk forConcerta / RitalinGeneric name here: MetilfenidatoControlled (Rx)

Controlled substance that needs a special prescription form. Tradea LP is a local extended-release alternative.

NaproxenNSAIDAsk forFlanaxGeneric name here: NaproxenoOTC / Rx

Some strengths need a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

Diclofenac (topical gel)NSAID, topical (pain-relief gel)Ask forVoltaren EmulgelGeneric name here: Diclofenaco (gel)OTC
FexofenadineAntihistamine, non-sedatingAsk forAllegraGeneric name here: FexofenadinaOTC
GuaifenesinExpectorant (chesty cough)Ask forRobitussinGeneric name here: GuaifenesinaOTC
DextromethorphanCough suppressant (dry cough)Ask forSold generic as "Dextrometorfano"OTC / Rx

Most cough products with it are sold without a prescription; some need one. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

Oxymetazoline (nasal spray)Nasal decongestant sprayAsk forAfrinGeneric name here: OximetazolinaOTC
Bismuth subsalicylateUpset stomach / traveler’s diarrheaAsk forPepto-BismolGeneric name here: Subsalicilato de bismutoOTC
Calcium carbonate (antacid)Antacid (heartburn)Ask forTumsGeneric name here: Carbonato de calcioOTC
SimeticoneAnti-gas (bloating)Ask forSold generic as "Simeticona"OTC / Rx

Most products are sold without a prescription; some need one. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

Oral rehydration saltsRehydration (diarrhea, heat, vomiting)Ask forElectrolit / PedialyteGeneric name here: Electrolitos orales (suero oral)OTC
BisacodylLaxative, stimulantAsk forDulcolaxGeneric name here: BisacodiloOTC
Polyethylene glycol 3350 (macrogol)Laxative, osmoticAsk forContumaxGeneric name here: Macrogol (polietilenglicol)OTC
MeclozineAntiemetic / motion sicknessAsk forBonadoxinaGeneric name here: MeclozinaRx only

Bonadoxina also contains vitamin B6. Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

Hydrocortisone (cream)Mild steroid cream (itch, rash, bites)Ask forSold generic as "Hidrocortisona crema"Rx only

Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

ClotrimazoleAntifungal cream (athlete’s foot, yeast)Ask forCanestenOTC
Bacitracin / Neomycin / Polymyxin B (antibiotic ointment)Topical antibiotic (cuts and scrapes)Ask forNeosporin DérmicoGeneric name here: Bacitracina / Neomicina / Polimixina BRx only

Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee. Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

DoxylamineSleep aid (sedating antihistamine)Ask forNot sold hereUnavailable

Only registered combined with vitamin B6 as Bonjesta, a prescription medicine for pregnancy nausea. There is no doxylamine sleep aid.

Levonorgestrel (emergency contraception)Emergency contraceptiveAsk forPostdayNo Rx: Ask Pharmacist
Atovaquone / ProguanilAntimalarial (prevention)Ask forMalaroneGeneric name here: Atovacuona / ProguanilRx only

Stock can be patchy, so bringing your full course from home is safer.

DoxycyclineAntibiotic, tetracycline (also malaria prevention)Ask forVibramicinaGeneric name here: DoxiciclinaRx only

Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

AzithromycinAntibiotic, macrolide (traveler’s diarrhea)Ask forAzitrocinGeneric name here: AzitromicinaRx only

Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

CiprofloxacinAntibiotic, fluoroquinolone (traveler’s diarrhea)Ask forCiproxinaGeneric name here: CiprofloxacinoRx only

Counterfeit and substandard products are a known risk in Mexico. If you can, get this at home before you travel.

AcetazolamideAltitude sickness preventionAsk forSold generic as "Acetazolamida"Rx only

Needs a prescription. Many pharmacies have a doctor’s office next door that can examine you and prescribe on the spot for a small fee.

Scopolamine (motion-sickness patch)Antiemetic patch (motion sickness)Ask forNot sold hereUnavailable

The hyoscine tablets sold here (butilhioscina) are for stomach cramps, not motion sickness.

OndansetronAntiemetic (nausea and vomiting)Ask forZofranRx only
Epinephrine (adrenaline auto-injector)Emergency treatment for severe allergic reactionsAsk forNot sold hereUnavailable

Mexico’s register has epinephrine only as hospital ampoules and in dental anaesthetics, with no auto-injector pen. Bring your own.