Rx Abroad
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Destination · GB

United Kingdom

What 82 common medicines are sold as in United Kingdom, and whether you can buy them over the counter. Take extra care with anything controlled or banned if you're bringing your own.

Entry summary

  • Controlled (Rx)6
  • Rx only44
  • OTC / Rx3
  • No Rx: Ask Pharmacist10
  • OTC15
  • Unavailable4
MedicineAsk forStatus
ParacetamolAnalgesic / antipyreticAsk forPanadolOTC
IbuprofenNSAIDAsk forNurofenOTC
LoratadineAntihistamine, non-sedatingAsk forClaritynOTC

Spelled "Clarityn" in the UK, not "Claritin".

CetirizineAntihistamine, non-sedatingAsk forPiriteze / ZirtekOTC
DiphenhydramineAntihistamine, sedatingAsk forNytol (sold as a sleep aid, not for allergy)No Rx: Ask Pharmacist

UK "Benadryl" is a different medicine (acrivastine or cetirizine). Diphenhydramine is sold as a sleep aid, under Nytol and pharmacy own-brand names.

Source: medxdrg.com ↗
LoperamideAntidiarrhealAsk forImodiumOTC
OmeprazoleProton pump inhibitorAsk forPyrocalm Control (OTC) / Losec (Rx)OTC / Rx

Losec itself has never held a UK OTC licence and remains prescription-only; the branded OTC product is Pyrocalm Control 20mg, sold in pharmacies and supermarkets for a maximum 14-day course.

PseudoephedrineDecongestantAsk forSudafedNo Rx: Ask Pharmacist

Pharmacy-only, with purchase limits.

MelatoninSleep aid / hormoneAsk forCircadinRx only

Regulated as a medicine, not a supplement, even at low doses. Bringing your own is often more reliable than buying it locally.

Source: ukmeds.co.uk ↗
DimenhydrinateAntiemetic / motion sicknessAsk forNot sold hereUnavailable

Kwells (hyoscine) or Stugeron (cinnarizine) cover this use. Dimenhydrinate is not a standard over-the-counter medicine in UK pharmacies; the only dimenhydrinate products listed are prescription-only. Boots and Superdrug stock hyoscine, cinnarizine or meclozine (Sea-Legs) travel-sickness tablets instead.

AmoxicillinAntibiotic, penicillinAsk forSold genericRx only
MetforminAntidiabetic, biguanideAsk forSold genericRx only
SertralineSSRI antidepressantAsk forLustralRx only

Sold as "Lustral", not "Zoloft", in the UK.

Source: drugs.com ↗
SalbutamolBronchodilator, inhaledAsk forVentolinRx only

Ventolin is prescription-only in the UK.

AtorvastatinStatin (cholesterol)Ask forLipitor (mostly sold generic now)Rx only
LevothyroxineThyroid hormone (hypothyroidism)Ask forSold generic; also historically "Eltroxin"Rx only
LisinoprilACE inhibitor (blood pressure)Ask forSold genericRx only
AmlodipineCalcium channel blocker (blood pressure)Ask forIstin (mostly sold generic)Rx only
MetoprololBeta blocker (blood pressure/heart)Ask forBetaloc (mostly sold generic)Rx only
LosartanARB (blood pressure)Ask forSold genericRx only
GabapentinNerve pain / anticonvulsantAsk forNeurontin (mostly sold generic)Controlled (Rx)

A Class C controlled substance in the UK since 2019 because of rising misuse. Expect controlled-drug handling: harder refills and stricter pharmacy rules.

RosuvastatinStatin (cholesterol)Ask forCrestor (mostly sold generic)Rx only
PantoprazoleProton pump inhibitorAsk forSold genericRx only
EscitalopramSSRI antidepressantAsk forCipralexRx only

Still sold by Lundbeck in the UK.

Amphetamine / DextroamphetamineStimulant (ADHD), controlled substanceAsk forAmfexa (dexamfetamine)Controlled (Rx)

Adderall’s mixed amphetamine salts are not licensed in the UK; dexamfetamine is the closest equivalent and is a controlled drug.

HydrochlorothiazideDiuretic (blood pressure)Ask forSold generic, often combined with other agentsRx only
BupropionAtypical antidepressant / smoking cessationAsk forZybanRx only

Sold in the UK mainly as a stop-smoking aid, not as an antidepressant. A pharmacist may not recognize "Wellbutrin". Ask for Zyban, and say you take it for depression if that is why.

FluoxetineSSRI antidepressantAsk forSold generic (formerly Prozac)Rx only
SemaglutideGLP-1 agonist (diabetes/weight)Ask forOzempic / WegovyRx only
MontelukastLeukotriene modifier (asthma/allergy)Ask forSingulair (mostly sold generic)Rx only
TrazodoneAntidepressant (commonly used off-label for sleep)Ask forSold genericRx only

Molipaxin brand was discontinued in the UK.

SimvastatinStatin (cholesterol)Ask forZocor (mostly sold generic)Rx only
TamsulosinAlpha blocker (enlarged prostate)Ask forFlomaxtra XLRx only

Still sold by Astellas Pharma in the UK.

Hydrocodone / Paracetamol combinationOpioid analgesic combination, controlled substanceAsk forNot sold hereUnavailable

Not licensed in the UK. It isn’t on the NHS medicine list. British doctors prescribe codeine, tramadol or oxycodone when an opioid is needed.

FluticasoneCorticosteroid (nasal spray / inhaler)Ask forPirinase Hayfever (nasal spray, OTC) / Flixotide (inhaler, Rx)OTC / Rx

Flixonase nasal spray is prescription-only in the UK. The hay fever spray sold without a prescription is Pirinase (also Nasofan Allergy); fluticasone inhalers for asthma need a prescription.

MeloxicamNSAID (arthritis)Ask forSold genericRx only

The Mobic brand appears to have been discontinued. The UK electronic Medicines Compendium now lists only generic meloxicam.

ApixabanAnticoagulant (blood thinner)Ask forEliquisRx only
FurosemideLoop diureticAsk forSold genericRx only
Insulin GlargineLong-acting insulinAsk forLantusRx only
Insulin LisproRapid-acting insulinAsk forHumalogRx only
Insulin AspartRapid-acting insulinAsk forNovoRapid / FiaspRx only
Insulin Human (Regular)Short-acting insulinAsk forActrapid / Humulin SRx only
Insulin Isophane (NPH)Intermediate-acting insulinAsk forInsulatard / Humulin IRx only
Insulin DetemirLong-acting insulinAsk forLevemirRx only

The maker is withdrawing Levemir worldwide, so stock may be limited. Other long-acting insulins sold here: glargine (Lantus) and degludec (Tresiba).

Insulin DegludecLong-acting insulinAsk forTresibaRx only
DuloxetineSNRI antidepressantAsk forSold genericRx only

Cymbalta brand was discontinued in the UK (listed discontinued on the electronic Medicines Compendium, last updated July 2024); generic duloxetine remains available.

FamotidineH2 blocker (acid reflux)Ask forSold genericRx only

Famotidine is prescription-only in the UK.

EmpagliflozinSGLT2 inhibitor (diabetes)Ask forJardianceRx only
CarvedilolBeta blocker (heart failure / blood pressure)Ask forSold genericRx only

The Eucardic brand appears to have been discontinued. The UK electronic Medicines Compendium now lists only generic carvedilol.

TramadolOpioid analgesic, controlled substanceAsk forSold genericControlled (Rx)

A Schedule 3 controlled drug in the UK since 2014. Prescription-only, with controlled-drug handling rules.

AlprazolamBenzodiazepine (anxiety), controlled substanceAsk forXanaxControlled (Rx)

Licensed in the UK but not prescribed on the NHS, so it is only available on a private prescription.

PrednisoneCorticosteroid (anti-inflammatory)Ask forNot sold hereUnavailable

Prednisolone is used instead. The only prednisone product listed in the UK is an imported, unlicensed one (Decortin), prescription-only. Prednisolone is the standard UK equivalent; a UK doctor would prescribe that.

ClopidogrelAntiplatelet (blood thinner)Ask forPlavix (mostly sold generic)Rx only
Acetylsalicylic acid (Aspirin)NSAID / antiplateletAsk forAspirin / DisprinOTC

Pain-relief aspirin (300 mg) is sold without a prescription, on general sale or at the pharmacy counter. Some other aspirin products are prescription-only.

OxycodoneOpioid analgesic, controlled substanceAsk forOxyContinControlled (Rx)

Tightly controlled. Still sold by Napp Pharmaceuticals in the UK. In Canada the original OxyContin was withdrawn and replaced by OxyNEO.

MethylphenidateStimulant (ADHD), controlled substanceAsk forConcerta / RitalinControlled (Rx)
NaproxenNSAIDAsk forFeminax UltraNo Rx: Ask Pharmacist

Without a prescription, naproxen is sold only as Feminax Ultra, for period pain, from the pharmacy counter. Other naproxen tablets are prescription-only.

Diclofenac (topical gel)NSAID, topical (pain-relief gel)Ask forVoltarolOTC

Voltarol Back & Muscle Pain Relief gel is on general sale; the other Voltarol gels are pharmacy-only, and the tablets and suppositories need a prescription.

FexofenadineAntihistamine, non-sedatingAsk forAlleviaOTC

Allevia 120 mg is sold without a prescription; Telfast and the 180 mg strength need one.

GuaifenesinExpectorant (chesty cough)Ask forBenylin Chesty Coughs / Robitussin Chesty CoughOTC
DextromethorphanCough suppressant (dry cough)Ask forBenylin Dry Coughs / Robitussin Dry CoughNo Rx: Ask Pharmacist
Oxymetazoline (nasal spray)Nasal decongestant sprayAsk forVicks SinexOTC
Bismuth subsalicylateUpset stomach / traveler’s diarrheaAsk forPepto-BismolOTC
Calcium carbonate (antacid)Antacid (heartburn)Ask forRennieOTC

Rennie also contains magnesium carbonate.

SimeticoneAnti-gas (bloating)Ask forWindSetlersOTC
Oral rehydration saltsRehydration (diarrhea, heat, vomiting)Ask forDioralyteOTC
BisacodylLaxative, stimulantAsk forDulcolaxOTC
Polyethylene glycol 3350 (macrogol)Laxative, osmoticAsk forMovicol / LaxidoNo Rx: Ask Pharmacist

Called "macrogol" outside the US.

MeclozineAntiemetic / motion sicknessAsk forSea-Legs / TraveleezeNo Rx: Ask Pharmacist

Sold for motion sickness without a prescription. Hyoscine (Kwells) and cinnarizine (Stugeron) are the more common choices.

Hydrocortisone (cream)Mild steroid cream (itch, rash, bites)Ask forHC45No Rx: Ask Pharmacist
ClotrimazoleAntifungal cream (athlete’s foot, yeast)Ask forCanestenNo Rx: Ask Pharmacist

Canesten creams are mostly pharmacy medicines; the athlete’s foot cream is also on general sale.

Bacitracin / Neomycin / Polymyxin B (antibiotic ointment)Topical antibiotic (cuts and scrapes)Ask forFucidin / Bactroban (Rx)Rx only

Fucidin is fusidic acid and Bactroban is mupirocin: different antibiotics for the same use. Antibiotic creams need a prescription in the UK. Without one, antiseptic creams such as Savlon or Germolene are sold.

DoxylamineSleep aid (sedating antihistamine)Ask forNot sold hereUnavailable

Nytol (diphenhydramine) is the usual sleep aid. Only licensed in combinations: with vitamin B6 for pregnancy nausea (Xonvea, prescription-only) and in some codeine painkillers.

Levonorgestrel (emergency contraception)Emergency contraceptiveAsk forLevonelleNo Rx: Ask Pharmacist
Atovaquone / ProguanilAntimalarial (prevention)Ask forMalarone (Rx) / Maloff Protect (pharmacy)OTC / Rx

Maloff Protect can be sold by a pharmacist without a prescription after a short consultation.

DoxycyclineAntibiotic, tetracycline (also malaria prevention)Ask forSold genericRx only
AzithromycinAntibiotic, macrolide (traveler’s diarrhea)Ask forSold genericRx only
CiprofloxacinAntibiotic, fluoroquinolone (traveler’s diarrhea)Ask forCiproxinRx only
AcetazolamideAltitude sickness preventionAsk forDiamoxRx only
Scopolamine (motion-sickness patch)Antiemetic patch (motion sickness)Ask forScopoderm (patch) / Kwells (tablets)No Rx: Ask Pharmacist

Both are pharmacy medicines: ask the pharmacist, no prescription needed. Called hyoscine hydrobromide in the UK.

OndansetronAntiemetic (nausea and vomiting)Ask forZofranRx only
Epinephrine (adrenaline auto-injector)Emergency treatment for severe allergic reactionsAsk forEpiPen / JextRx only

Called "adrenaline" outside North America.